The 2-Minute Rule for ketamine new york times
Metabolism Ketamine is metabolized through N-dealkylation towards the Energetic metabolite norketamine primarily by CYP2B6 and CYP3A4 and to a lesser extent by other CYP enzymes. Norketamine undergoes hydroxylation of your cyclohexone ring to type hydroxynorketamine compounds by using CYP-dependent pathways, which are conjugated with glucuronic aci